Of the articles identified, were selected for review. The new data were added to the data on the comparison available in the Cochrane review. We did not exclude studies in which subjects received oxytocin augmentation after cervical ripening. We performed a best evidence review of the literature supporting each method.
We preferentially included high quality systematic reviews or large randomised trials. If five or more randomised controlled trials involving a method of induction were published subsequent to the search date of the most recent included systematic review or were "awaiting classification" in the systematic review, we conducted meta-analyses of the primary outcomes reported in these studies.
However, there is insufficient evidence to recommend that high-dose regimens are advised routinely for women with delay in the first stage of labour.
The following outcomes were not evaluated in the included studies: We identified abstracts and reviewed full text articles. Several factors may influence the choice of method for induction of labour including cervical and membrane status, parity, and patient and provider preference.
The search covered the period from January to November We conducted this review to summarize the best evidence available for pregnant women requiring induction of labor in the third trimester of pregnancy with a live fetus.
However, for comparisons of methods with each other, we followed the pre-specified hierarchy used for the series of induction of labour Cochrane Reviews and arranged labour induction methods in that specific order [ 2 ].
Further research should evaluate the effect of high-dose regimens of oxytocin for women delayed in labour and should include maternal and neonatal outcomes as well as the effects on women.
Previous article in issue. Read the full abstract For neonatal outcomes, there was no significant difference between groups for Apgar scores, umbilical cord pH, admission to special care baby unit, or neonatal mortality. Methods We conducted a comprehensive literature search of the English language literature using Medline and the Cochrane Database of Systematic Reviews.
Dinoprost; Carboprost or hemabate; prostin, oxytocin, misoprostol, prostaglandins, membrane sweeping or membrane stripping, amniotomy, balloon catheter or Foley catheter, hygroscopic dilators, laminaria, dilapan, saline injection, nipple stimulation, intercourse, acupuncture, castor oil, herbs".
Three studies were randomised controlled trials and one trial was a quasi-randomised study. Four review authors undertook assessment of trial eligibility, risk of biasand data extraction independently.
We compared each method with placebo and with other methods of labor induction. In this paper we review the evidence for effectiveness of pharmacologic, mechanical, investigational, and complementary and alternative medicine means of third trimester labour induction. Two authors, VR and UP extracted data independently.
Only one trial reported on the possible effect on women. We identified additional articles for consideration of inclusion through cross checks of relevant bibliographies.
Results We included 46 full text articles. Some evidence suggests that up to one-third of women in their first labour experience delay.
Enter terms Oxytocin in high versus low doses for augmentation of delayed labour Women have different lengths of labour, with first labours lasting on average eight hours and unlikely to last more than 18 hours and second and subsequent labours lasting an average of five hours and unlikely to last more than 12 hours.
However, there are potentially harmful side effects as oxytocin may cause the uterus to contract too quickly, and the baby to become distressed. Abstract Background Rates of labour induction are increasing.
The separation of low- and high-dose regimens is based on an arbitrary decision.This paper reviews the wide effects of oxytocin and its key role in well-being. Methods Studies were identified through Medline, Pubmed, and PsychINFO search of the English-language literature from the past sixty years ( to ) using the key word “oxytocin” in human studies.
In a retrospective review, amongst a cohort of term women undergoing induction of labor with subsequent vaginal deliveries, obese women (BMI > 40 kg/ m 2) required more oxytocin than lean women during the first stage of labor when matched for parity, diabetes, epidural use, birth weight, pre-induction dilatation, and station .
Oxytocin is a hormone that stimulates uterine contractions in labour and is given to women who are slow to progress in labour.
By giving oxytocin to all women with epidurals during labour, the rate of operative deliveries, and the associated complications, could be reduced. Breastfeeding Outcomes After Oxytocin Use During Childbirth: An Integrative Review.
Authors. Despite widespread use of exogenous synthetic oxytocin during the birth process, few studies have examined the effect of this drug on breastfeeding.
This article examines the literature on the role of exogenous oxytocin on breastfeeding in humans. Literature review The objective of this literature review is to assess and investigate available literature studying the timing of oxytocin during the third stage of labour.
I searched the Maternity and Infant Care, the Cochrane Library and Pubmed databases and details of the search strategies can be found in appendix 1. Higher-dose regimens of oxytocin (4 mU per minute or more) were associated with a reduction in the length of labour and in caesarean section, and an increase in spontaneous vaginal ultimedescente.comr, there is insufficient evidence to recommend that high-dose regimens are advised routinely for women with delay in the first stage of labour.Download